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The antagonism of histamine-induced tracheal and bronchial muscle contraction by diphenhydramine: effect of maturation.
Airway reactivity in spontaneously breathing unanaesthetized female guinea-pigs was significantly reduced as a consequence of maturation. Threshold doses to histamine (% w/v base) were 0.08% +/- .01 and 0.27% +/- .04 in immature (110 g +/- 2; 1 week old) and mature (837 g +/- 29; 4 months old) anima...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1987088/ https://ncbi.nlm.nih.gov/pubmed/6150738 |
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