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Recovery of beta-adrenoceptors and cyclic AMP response after long term treatment of intact heart cells with beta-blockers.

We have studied the recovery of receptor binding and of isoprenaline-stimulated cyclic AMP responses after chronic (2-5 days) exposure of tissue-cultured living rat heart cells to several beta-adrenoceptor antagonists. Most experiments were performed with [3H]- (+/-)-carazolol and [3H]-(+/-)-CGP 121...

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Autors principals: Becker, C., Porzig, H.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987018/
https://ncbi.nlm.nih.gov/pubmed/6146370
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