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Pharmacological studies into cyclo-oxygenase, lipoxygenase and phospholipase in smooth muscle contraction in the isolated trachea.
Indomethacin (1 microM) enhanced histamine-induced contractions in pig and guinea-pig isolated tracheae. Mepacrine (30-50 microM) abolished this effect of indomethacin suggesting that contractile metabolites of arachidonate are involved in the response to indomethacin. Mepacrine (100 microM) in the...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1987013/ https://ncbi.nlm.nih.gov/pubmed/6430374 |
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