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The control of 86Rb efflux from rat isolated pancreatic islets by the sulphonylureas tolbutamide and glibenclamide.

The efflux of 86Rb from rat isolated pancreatic islets preloaded with the isotope and perifused in vitro, has been used to monitor the effects of sulphonylureas on the potassium permeability, Pk, of pancreatic beta-cells. Tolbutamide (5 microM to 5 mM) had a dual effect, causing initially a decrease...

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Detalhes bibliográficos
Main Authors: Matthews, E. K., Shotton, P. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987011/
https://ncbi.nlm.nih.gov/pubmed/6430377
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