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Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling.

The effects of the acute and chronic administration of the beta-carboline benzodiazepine receptor ligand, FG 7142 were studied in mice. On acute administration FG 7142 (at doses between 10 and 40 mg kg-1) lowered seizure thresholds to infused pentylenetetrazol (PTZ) but showed an unusual dose-respon...

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Autores principales: Little, H. J., Nutt, D. J., Taylor, S. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1984
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986992/
https://ncbi.nlm.nih.gov/pubmed/6097329
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