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Antagonism of Ca2+ and other actions of verapamil in guinea-pig isolated trachealis.

In trachealis bathed by a K+-rich, Ca2+-free physiological salt solution, calcium chloride (CaCl2) at 0.01 to 10 mmol l-1 evoked concentration-dependent spasm. Verapamil (0.1 to 10 mumol l-1) was an effective antagonist of CaCl2. Spasm evoked by acetylcholine, histamine, potassium chloride (KCl) and...

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Autores principales: Foster, R. W., Okpalugo, B. I., Small, R. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1984
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986847/
https://ncbi.nlm.nih.gov/pubmed/6582986
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