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Polyadenylation site choice in yeast is affected by competition between Npl3 and polyadenylation factor CFI

Multiple steps in mRNA processing and transcription are coupled. Notably, the processing of mRNA 3′ ends is linked to transcription termination by RNA polymerase II. Previously, we found that the yeast hnRNP protein Npl3 can negatively regulate 3′ end mRNA formation and termination at the GAL1 gene....

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Библиографические подробности
Главные авторы: Bucheli, Miriam E., He, Xiaoyuan, Kaplan, Craig D., Moore, Claire L., Buratowski, Stephen
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986811/
https://ncbi.nlm.nih.gov/pubmed/17684230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.607207
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