A role for histone deacetylase activity in HDAC1-mediated transcriptional repression
Treatment of mammalian cells with small molecule histone deacetylase (HDAC) inhibitors induces changes in the transcription of specific genes. These changes correlate directly with an increase in the acetylation levels of all four core histones in vivo. Antibodies directed against endogenous HDAC1,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520398/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3519 |
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