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Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region
The juxtamembrane (JM) regions of several receptor tyrosine kinases are involved in autoinhibitory interactions that maintain the low basal activity of the receptors; mutations can give rise to constitutive kinase activity and signaling. In this report, we show that the JM region of the human insuli...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1986766/ https://ncbi.nlm.nih.gov/pubmed/17586502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.06.014 |
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