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Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells

The factors involved in the differentiation of memory CD4 T cells from naïve precursors are poorly understood. We developed a system to examine the effect of increased competition for antigen by CD4 T cells on the generation of memory in response to infection with a recombinant vesicular stomatitis...

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Detalhes bibliográficos
Main Authors: Blair, David A., Lefrançois, Leo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986610/
https://ncbi.nlm.nih.gov/pubmed/17827281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703767104
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