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The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos

Caenorhabditis elegans embryos establish cortical domains of PAR proteins of reproducible size before asymmetric cell division. The ways in which the size of these domains is set remain unknown. Here we identify the GTPase-activating proteins (GAPs) RGA-3 and RGA-4, which regulate the activity of th...

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Autors principals: Schonegg, Stephanie, Constantinescu, Alexandru T., Hoege, Carsten, Hyman, Anthony A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986598/
https://ncbi.nlm.nih.gov/pubmed/17848508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706941104
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