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Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation

The mechanisms that regulate hematopoietic stem cell (HSC) fate decisions between proliferation and multilineage differentiation are unclear. Members of the Wnt family of ligands that activate the canonical Wnt signaling pathway, which utilizes β-catenin to relay the signal, have been demonstrated t...

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Detalles Bibliográficos
Main Authors: Nemeth, Michael J., Topol, Lilia, Anderson, Stacie M., Yang, Yingzi, Bodine, David M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986571/
https://ncbi.nlm.nih.gov/pubmed/17881570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704747104
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