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Hepatoprotection via the IL-6/Stat3 pathway
Stat3 is a vital transcription factor that is activated downstream of the gp130 receptor, primarily via IL-6 signaling in adult liver. A new study demonstrates that Stat3 provides hepatoprotection against Fas-mediated apoptotic liver damage by two mechanisms: direct inactivation of caspases and redu...
Wedi'i Gadw mewn:
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Clinical Investigation
2003
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC198534/ https://ncbi.nlm.nih.gov/pubmed/14523032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319974 |
| Tagiau: |
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