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Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen

E-selectin and P-selectin on dermal postcapillary venules play critical roles in the migration of effector T cells into inflamed skin. P-selectin glycoprotein ligand-1 (PSGL-1) modified by α1,3-fucosyltransferase is the principal selectin ligand on skin-homing T cells and is required for effector T...

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Autori principali: Dimitroff, Charles J., Kupper, Thomas S., Sackstein, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC198531/
https://ncbi.nlm.nih.gov/pubmed/14523038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319220
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