Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans

Cryptococcus neoformans is a fungal pathogen that, after inhalation, can disseminate to the brain. Host alveolar macrophages (AMs) represent the first defense against the fungus. Once phagocytosed by AMs, fungal cells are killed by a concerted mechanism, involving the host-cellular response. If the...

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Main Authors: Luberto, Chiara, Martinez-Mariño, Beatriz, Taraskiewicz, Daniel, Bolaños, Benjamin, Chitano, Pasquale, Toffaletti, Dena L., Cox, Gary M., Perfect, John R., Hannun, Yusuf A., Balish, Edward, Poeta, Maurizio Del
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC198528/
https://ncbi.nlm.nih.gov/pubmed/14523045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318309
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