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Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

Matrix metalloproteinases (MMPs) classically have been implicated in basement membrane destruction associated with late-stage tumor cell invasion and metastasis. However, recent studies have demonstrated that one MMP family member, matrilysin, is expressed in a high percentage of early-stage human c...

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Autors principals: Wilson, Carole L., Heppner, Kathleen J., Labosky, Patricia A., Hogan, Brigid L. M., Matrisian, Lynn M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19803/
https://ncbi.nlm.nih.gov/pubmed/9037065
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