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Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function

Allogeneic bone marrow transplant recipients often exhibit a graft-versus-host-disease (GVHD)-associated immune deficiency that can be prolonged and lead to life-threatening infections. We have examined the role of donor T cell-mediated cytotoxic function in the development of GVHD-associated immune...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Baker, Matthew B., Riley, Richard L., Podack, Eckhard R., Levy, Robert B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037059/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1366
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