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Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung

How effectively and quickly endothelial caveolae can transcytose in vivo is unknown, yet critical for understanding their function and potential clinical utility. Here we use quantitative proteomics to identify aminopeptidase P (APP) concentrated in caveolae of lung endothelium. Electron microscopy...

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Sonraí Bibleagrafaíochta
Main Authors: Oh, Phil, Borgström, Per, Witkiewicz, Halina, Li, Yan, Borgström, Bengt J, Chrastina, Adrian, Iwata, Koji, Zinn, Kurt R, Baldwin, Richard, Testa, Jacqueline E, Schnitzer, Jan E
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1979160/
https://ncbi.nlm.nih.gov/pubmed/17334358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1292
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