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High-resolution functional mapping of a cloned gene by genetic footprinting

We describe an efficient method for introducing and analyzing a comprehensive set of mutations in a cloned gene to map its functional organization. The technique, genetic footprinting, uses a retroviral integrase to generate a comprehensive library of mutants, each of which bears a single insertion...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Singh, Ila R., Crowley, Rachel Adams, Brown, Patrick O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC19786/
https://ncbi.nlm.nih.gov/pubmed/9037048
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