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IL-2 and Autocrine IL-4 Drive the In Vivo Development of Antigen-Specific Th2 T Cells Elicited by Nematode Parasites

The intestinal nematode parasite, Nippostrongylus brasiliensis, triggers potent type 2 immunity. Using OVA peptide as a model Ag, we have examined the adjuvant effects of this parasite on the in vivo development of Ag-specific Th2 cells from naive DO11.10 T cells. Our findings show that Th2 cells ca...

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Autors principals: Liu, Zhugong, Liu, Qian, Hamed, Hossein, Anthony, Robert M., Foster, Anthony, Finkelman, Fred D., Urban, Joseph F., Gause, William C.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978543/
https://ncbi.nlm.nih.gov/pubmed/15699158
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