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Activation of ERK1/2 pathway mediates oxidant-induced decreases in mitochondrial function in renal cells

Previously, we showed that oxidant exposure in renal proximal tubular cells (RPTC) induces mitochondrial dysfunction mediated by PKC-ε. This study examined the role of ERK1/2 in mitochondrial dysfunction induced by oxidant injury and whether PKC-ε mediates its effects on mitochondrial function throu...

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Detalhes bibliográficos
Main Authors: Nowak, Grażyna, Clifton, Ginger L., Godwin, Malinda L., Bakajsova, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978509/
https://ncbi.nlm.nih.gov/pubmed/16705147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00219.2005
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