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Sustained contraction and loss of NO production in TGFβ(1)-treated endothelial cells

BACKGROUND AND PURPOSE: Transforming growth factor β(1) (TGFβ(1)) is generated in atherosclerotic and injured vessel walls. We examined whether the endothelial-to-mesenchymal transdifferentiation induced by TGFβ(1) affects endothelial functions. EXPERIMENTAL APPROACH: Bovine aortic endothelial cells...

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Autori principali: Watanabe, M, Oike, M, Ohta, Y, Nawata, H, Ito, Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978430/
https://ncbi.nlm.nih.gov/pubmed/16967050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706883
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