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Propranolol causes a paradoxical enhancement of cardiomyocyte foetal gene response to hypertrophic stimuli
BACKGROUND AND PURPOSE: Pathological cardiac hypertrophy is associated with the expression of a gene profile reminiscent of foetal development. The non selective β-adrenoceptor antagonist propranolol is able to blunt cardiomyocyte hypertrophic response in pressure-overloaded hearts. It remains to be...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978260/ https://ncbi.nlm.nih.gov/pubmed/17592507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707350 |
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