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Therapeutic concentrations of raloxifene augment nitric oxide-dependent coronary artery dilatation in vitro

BACKGROUND AND PURPOSE: Raloxifene improves cardiovascular function. This study examines the hypothesis that therapeutic concentrations of raloxifene augment endothelium-dependent relaxation via up-regulation of eNOS expression and activity in porcine coronary arteries. EXPERIMENTAL APPROACH: Isomet...

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Main Authors: Leung, F P, Yung, L M, Leung, H S, Au, C L, Yao, X, Vanhoutte, P M, Laher, I, Huang, Y
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978259/
https://ncbi.nlm.nih.gov/pubmed/17618301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707387
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