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Progressive Biliary Destruction is Independent of a Functional Tumor Necrosis Factor-alpha Pathway in a Murine Model of Biliary Atresia

Rhesus rotavirus (RRV)-inoculated neonatal BALB/c mice develop an immune mediated inflammation of both extra- and intrahepatatic bile ducts which progresses to biliary obstruction and death by 3 weeks of age. The livers of diseased animals demonstrate increased numbers of T-lymphocytes along with el...

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Detalhes bibliográficos
Main Authors: Tucker, Rebecca M., Hendrickson, Richard J., Mukaida, Naofumi, Gill, Ronald G., Mack, Cara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978183/
https://ncbi.nlm.nih.gov/pubmed/17425419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2006.0088
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