Crystal Structures of the Pilus Retraction Motor PilT Suggest Large Domain Movements and Subunit Cooperation Drive Motility

PilT is a hexameric ATPase required for bacterial Type IV pilus retraction and surface motility. Crystal structures of ADP and ATP-bound Aquifex aeolicus PilT at 2.8 and 3.2 Å resolution show N-terminal PAS-like and C-terminal RecA-like ATPase domains followed by a set of short C-terminal helices. T...

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Autori principali: Satyshur, Kenneth A., Worzalla, Gregory A., Meyer, Lorraine S., Heiniger, Erin K., Aukema, Kelly G., Misic, Ana M., Forest, Katrina T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978094/
https://ncbi.nlm.nih.gov/pubmed/17355871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.01.018
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