Induction of soluble tumour necrosis factor receptors during treatment with interleukin-2.

Interleukin-2 (IL-2) treatment induces other cytokines such as tumour necrosis factor (TNF) TNF may mediate some of the anti-tumour activity of IL-2, but conversely, may contribute to its dose limiting toxicities. Cleaved extracellular domains of the p55 and the p75 TNF receptors (sTNF-R1 and R2) bi...

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Bibliographic Details
Main Authors: Miles, D. W., Aderka, D., Engelmann, H., Wallach, D., Balkwill, F. R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978036/
https://ncbi.nlm.nih.gov/pubmed/1333789
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