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Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells.

Two aspects of the aerobic metabolism of nitroimidazole markers for hypoxia were investigated. Several normal murine tissues which are likely to be well oxygenated bind misonidazole at rates comparable to those of hypoxic regions in tumours. The possibility that this aerobic activation occurs via an...

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Bibliografski detalji
Glavni autori: Parliament, M. B., Wiebe, L. I., Franko, A. J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978026/
https://ncbi.nlm.nih.gov/pubmed/1280990
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