131I-meta-iodobenzylguanidine therapy in neuroblastoma spheroids of different sizes.

Mathematical models have predicted that targeted radiotherapy of neuroblastoma with metaiodobenzylguanidine (mIBG) is less likely to cure small rather than large micrometastases if 131I is the conjugated radionuclide. This study uses multicellular tumour spheroids as an in vitro model to test the hy...

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Bibliographic Details
Main Authors: Gaze, M. N., Mairs, R. J., Boyack, S. M., Wheldon, T. E., Barrett, A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978020/
https://ncbi.nlm.nih.gov/pubmed/1457344
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