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Chromosomal localisation of two putative 11p oncosuppressor genes involved in human ovarian tumours.

In this study, 44 primary or metastatic human ovarian tumours were tested for allelic deletions on the short arm of chromosome 11. Analysis of 12 polymorphic loci by Southern blotting evidenced loss of heterozygosity (LOH) in at least one locus in 41% of cases. Moreover, two hot spots of deletions w...

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Autors principals: Viel, A., Giannini, F., Tumiotto, L., Sopracordevole, F., Visentin, M. C., Boiocchi, M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978017/
https://ncbi.nlm.nih.gov/pubmed/1360809
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