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High-dose tamoxifen as an enhancer of etoposide cytotoxicity. Clinical effects and in vitro assessment in p-glycoprotein expressing cell lines.

Twenty-six patients with relapsed or drug-resistant cancer were treated with a combination of oral etoposide (300 mg day-1 for 3 days) and high-dose oral tamoxifen as a potential modulator of drug resistance (480 or 720 mg day-1 for 6 days beginning 3 days before etoposide). One patient with relapse...

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Main Authors: Stuart, N. S., Philip, P., Harris, A. L., Tonkin, K., Houlbrook, S., Kirk, J., Lien, E. A., Carmichael, J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1992
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977984/
https://ncbi.nlm.nih.gov/pubmed/1358168
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