Increased expression and mutation of p53 in choroidal melanoma.

Using CM-1 antibody directed against the human p53 protein, high levels of mutant p53 protein expression were found in 12 out of 18 malignant choroidal melanomas. In contrast, we failed to observe elevated p53 expression, indicating the absence of p53 mutation in seven choroidal naevi, a potentially...

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Bibliografiske detaljer
Main Authors: Tobal, K., Warren, W., Cooper, C. S., McCartney, A., Hungerford, J., Lightman, S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977965/
https://ncbi.nlm.nih.gov/pubmed/1419633
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