Therapeutic effect of the gastrin receptor antagonist, CR2093 on gastrointestinal tumour cell growth.

The gastrin receptor antagonist, CR2093, competed with 125I-gastrin-17 (5 x 10(-10) M) for binding to gastrin receptors on the rat pancreatic adenocarcinoma, AR42J (CR2093 concentration inducing 50% of 125I-gastrin-17 binding (IC50) was 8 x 10(-5) M), on the human gastric adenocarcinoma, MKN45 (IC50...

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Bibliografiske detaljer
Main Authors: Watson, S. A., Crosbee, D. M., Morris, D. L., Robertson, J. F., Makovec, F., Rovati, L. C., Hardcastle, J. D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977787/
https://ncbi.nlm.nih.gov/pubmed/1616859
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