Fluorescence distribution and photodynamic effect of ALA-induced PP IX in the DMH rat colonic tumour model.

Aminolaevulinic acid (ALA) is the first committed step in haem synthesis. In the presence of excess ALA the natural regulatory feedback system is disrupted allowing accumulation of protoporphyrin IX (PP IX) the last intermediate product before haem, and an effective sensitiser. This method of endoge...

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Bibliografische gegevens
Hoofdauteurs: Bedwell, J., MacRobert, A. J., Phillips, D., Bown, S. G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1992
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977757/
https://ncbi.nlm.nih.gov/pubmed/1616853
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