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BW12C: effects on tumour hypoxia, tumour thermosensitivity and relative tumour and normal tissue perfusion in C3H mice.

BW12C (5-[2-formyl-3-hydroxypenoxyl] pentanoic acid) is an agent which stabilises oxyhaemoglobin and thus reduces oxygen delivery to tissues. It is of interest as a possible potentiator of bioreductive agents and/or hyperthermia. The increases in radiobiological hypoxic fraction of RIF-1 and KHT tum...

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Autors principals: Honess, D. J., Hu, D. E., Bleehen, N. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977694/
https://ncbi.nlm.nih.gov/pubmed/1911220
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