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c-src structure in human cancers with elevated pp60c-src activity.

We used RNAase protection and restriction fragment length polymorphism assays to detect activating mutations of c-src in a spectrum of human tumours. No mutations were detected at codons 98, 381, 444, and 530. We conclude that mutational activation is not the mechanism of enhancement of pp60c-src-sp...

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Bibliografische gegevens
Hoofdauteurs: Wang, P., Fromowitz, F., Koslow, M., Hagag, N., Johnson, B., Viola, M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1991
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977675/
https://ncbi.nlm.nih.gov/pubmed/1716952
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