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Transcriptional down-regulation of c-myc in human prostate carcinoma cells by the synthetic androgen mibolerone.

The mechanism of down-regulation of c-myc RNA associated with androgen-induced suppression of the transformed phenotype in the human prostate carcinoma cell line LNCaP was investigated. The synthetic androgen mibolerone (7 alpha-17 alpha-Dimethyl-19-nortestosterone) reversibly inhibits the prolifera...

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Detalhes bibliográficos
Main Authors: Wolf, D. A., Kohlhuber, F., Schulz, P., Fittler, F., Eick, D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977595/
https://ncbi.nlm.nih.gov/pubmed/1373070
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