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Evaluation of tumour and tissue distribution of porphyrins for use in photodynamic therapy.

A range of pure, monomeric porphyrins were synthesised and their localising capacities compared to HpD and Hp at 6 h and 24 h post injection in the mouse C6 intracerebral glioma model as well as in normal brain, skin, muscle, kidney, spleen, liver, lung and whole blood. The partition coefficients we...

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Main Authors: Woodburn, K. W., Stylli, S., Hill, J. S., Kaye, A. H., Reiss, J. A., Phillips, D. R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977589/
https://ncbi.nlm.nih.gov/pubmed/1558783
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