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Monoclonal antibody FW6 generated against a mucin-carbohydrate of human amniotic fluid recognises a colonic tumour-associated epitope.
Mucus glycoproteins of human amniotic fluid were used to generate a monoclonal antibody (MAb) FW6, which stained the intestine of a 24 week stage fetus. In adults, 76% of colonic adenocarcinomas (13/17) showed strong expression of the FW6 epitope, but it was not detected in the histologically normal...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Nature Publishing Group
1992
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1977553/ https://ncbi.nlm.nih.gov/pubmed/1373294 |
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