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Influence of tumour physico-chemical conditions on interleukin-2-stimulated lymphocyte proliferation.

The proliferative response of murine lymphocytes to interleukin-2 (IL-2) was examined under physico-chemical conditions present in solid tumours, namely low oxygen and glucose concentrations and acidic pH. Lymphocytes were cultured for four days in 30 U ml-1 IL-2 to simulate serum IL-2 concentration...

詳細記述

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書誌詳細
主要な著者: Loeffler, D. A., Juneau, P. L., Masserant, S.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977437/
https://ncbi.nlm.nih.gov/pubmed/1419598
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