P53 mutations in gastric carcinomas.

We carried out an immunohistochemical study and DNA analysis of 30 gastric carcinomas to evaluate p53 overexpression and allelic loss at 17p. The immunohistochemical study demonstrated immunoreactivity for p53 protein in four cases. Allelic loss for the pYNZ22.1 marker was detected in nine cases. In...

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Bibliographic Details
Main Authors: Seruca, R., David, L., Holm, R., Nesland, J. M., Fangan, B. M., Castedo, S., Sobrinho-Simões, M., Børresen, A. L.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977375/
https://ncbi.nlm.nih.gov/pubmed/1586599
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