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ras gene alterations in invasive and non-invasive rat bladder carcinomas induced by N-methyl-N-nitrosourea.

We have established a reliable method to induce invasive and non-invasive carcinomas in the heterotopically transplanted urinary bladder of rats by repeated injection of N-methyl-N-nitrosourea (MNU), and examined the alterations of the ras oncogenes and ras oncogene product (p21) in the induced tumo...

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Detalles Bibliográficos
Main Authors: Yura, Y., Azuma, M., Uchida, K., Momose, H., Oyasu, R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1991
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977327/
https://ncbi.nlm.nih.gov/pubmed/1854607
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