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Drug-target interactions: only the first step in the commitment to a programmed cell death?

The search for novel antitumour drugs has reached a plateau phase. The carcinomas remain almost as intractable as they did 40 years ago and the need for effective therapy is pressing. There is an argument that the current pharmacopoeia is sufficient but, to be effective, the biochemical mechanisms o...

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Autori principali: Dive, C., Hickman, J. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1991
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977304/
https://ncbi.nlm.nih.gov/pubmed/1854622
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