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Failure of systemic ketosis to control cachexia and the growth rate of the Walker 256 carcinosarcoma in rats.

The Walker 256 carcinosarcoma was shown to lack the enzyme 3-ketoacid CoA transferase. This suggests that ketone bodies cannot be used as a major substrate for the energy metabolism of this tumour. Systemic ketosis (1-2 mM acetoacetate plus 3-hydroxybutyrate) was induced both in tumour-bearing and i...

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Bibliographische Detailangaben
Hauptverfasser: Fearon, K. C., Tisdale, M. J., Preston, T., Plumb, J. A., Calman, K. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1985
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977175/
https://ncbi.nlm.nih.gov/pubmed/2861842
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