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Mutagenic and cytotoxic activity of doxorubicin and daunorubicin derivatives on prokaryotic and eukaryotic cells.

The mutagenic and cytotoxic activity of two newly synthesized doxorubicin derivatives and of one daunorubicin derivative were studied in V79 Chinese hamster cells and bacteria (Salmonella typhimurium and Escherichia coli). The results showed that all the compounds tested were cytotoxic and mutagenic...

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Bibliografiske detaljer
Main Authors: Babudri, N., Pani, B., Tamaro, M., Monti-Bragadin, C., Zunino, F.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1984
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976926/
https://ncbi.nlm.nih.gov/pubmed/6378238
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