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Hypoxic cells and in situ chemopotentiation of the nitrosoureas by misonidazole.

Intracerebral (i.c.) and subcutaneous (s.c.) 9L tumours were treated simultaneously with various doses of the nitrosoureas, BCNU or CCNU, and 2.5 mmol kg-1 of misonidazole (MISO). After 24 h, tumours were removed, dissociated into single cell suspensions and the cells plated for colony formation. In...

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Autors principals: Wheeler, K. T., Wallen, C. A., Wolf, K. L., Siemann, D. W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976835/
https://ncbi.nlm.nih.gov/pubmed/6733024
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