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Hypoxic cells and in situ chemopotentiation of the nitrosoureas by misonidazole.

Intracerebral (i.c.) and subcutaneous (s.c.) 9L tumours were treated simultaneously with various doses of the nitrosoureas, BCNU or CCNU, and 2.5 mmol kg-1 of misonidazole (MISO). After 24 h, tumours were removed, dissociated into single cell suspensions and the cells plated for colony formation. In...

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Bibliographic Details
Main Authors: Wheeler, K. T., Wallen, C. A., Wolf, K. L., Siemann, D. W.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1984
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976835/
https://ncbi.nlm.nih.gov/pubmed/6733024
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