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Mechanisms of tumour cell escape encountered in treating lymphocytic leukaemia with anti-idiotypic antibody.

Four patients with chronic lymphocytic leukaemia were treated by one or more infusions of polyclonal antibody specific for the immunoglobulin idiotype expressed on their leukaemic cells. The antibody was in the form of IgG from sheep antiserum. Three of the 4 cases showed a significant fall in blood...

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Main Authors: Gordon, J., Abdul-Ahad, A. K., Hamblin, T. J., Stevenson, F. K., Stevenson, G. T.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976721/
https://ncbi.nlm.nih.gov/pubmed/6722005
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