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Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae

DNA double-strand breaks can be repaired by illegitimate recombination without extended sequence homology. A distinct mechanism namely microhomology-mediated recombination occurs between a few basepairs of homology that is associated with deletions. Ionizing radiation and restriction enzymes have be...

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Detalhes bibliográficos
Main Authors: Chan, Cecilia Y., Kiechle, Markus, Manivasakam, Palaniyandi, Schiestl, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976441/
https://ncbi.nlm.nih.gov/pubmed/17652322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm442
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