Nuclear Heat Shock Protein 72 as a Negative Regulator of Oxidative Stress (Hydrogen Peroxide)-Induced HMGB1 Cytoplasmic Translocation and Release

In response to inflammatory stimuli (e.g., endotoxin, proinflammatory cytokines) or oxidative stress, macrophages actively release a ubiquitous nuclear protein, high-mobility group box 1 (HMGB1), to sustain an inflammatory response to infection or injury. In this study, we demonstrated mild heat sho...

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Hauptverfasser: Tang, Daolin, Kang, Rui, Xiao, Weimin, Jiang, Lei, Liu, Meidong, Shi, Yongzhong, Wang, Kangkai, Wang, Haichao, Xiao, Xianzhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976272/
https://ncbi.nlm.nih.gov/pubmed/17513788
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