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Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases
Terminal RNA uridylyltransferases (TUTases) catalyze template-independent UMP addition to the 3′ hydroxyl of RNA. TUTases belong to the DNA polymerase β superfamily of nucleotidyltransferases that share a conserved catalytic domain bearing three metal-binding carboxylate residues. We have previously...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976215/ https://ncbi.nlm.nih.gov/pubmed/17785418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704259104 |
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